Infant Feeding Practices in Transition: Breast Milk Intake, Complementary Feeding and Body Composition During Infancy

N/ACompletedNCT04020640

Mahidol University110 enrolled

Overview

Research Aim: We assessed human milk intakes of Thai infants during the first 6 months comparing exclusive (EBF), predominant (PBF) and partial (PartBF) breastfeeding. Methods: One-hundred and ten apparently healthy Thai lactating mother-infant pairs were followed from birth. Human milk intakes were determined at 6 weeks, 3 and 6 months, using the DTM method. Daily energy and protein intakes were assessed using 3-day non-consecutive 24-hour recalls. Socio-demographic characteristics were collected using a questionnaire. For comparisons among breastfeeding practices, one-way ANOVA with Tukey's post hoc test was used for normally distributed data, or Kruskal-Wallis Test with Mann-Whitney U Test for not normally distributed data.

Human milk intakes were comparable between the EBF and PBF infants during the first 6 months, and provided the sole source of energy and protein; infant formula largely replaced breast milk among PartBF infants.

Study Type

OBSERVATIONAL

Enrollment

110

Conditions

Breast Feeding

Interventions

no interventionOTHER

Measure human intake using stable isotope technique

Eligibility

Sex: ALLMin age: 2 WeeksMax age: 6 MonthsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Apparently healthy women aged 20-35 year * Had pre-pregnancy BMI in the normal range (18.5-25 kg/m2) * Planned to breastfeed their baby for at least 6 months * Being full term infants (gestational age 37-42 weeks) and singleton * Had normal birth weight (2,500 - 4,000 g) * Signed written informed consent to participate in the study Exclusion Criteria: * Infant: preterm; twin; low and high birth weight; congenital diseases * Mother: chronic diseases needed to get medicine and treatment; underweight and obesity * Mother and baby did not stay together throughout 12 months of infant age

Outcomes

Primary Outcomes

Human milk intake of Thai breastfed infants during the first 6 months using the dose-to-mother deuterium dilution method

assessed human milk intakes of Thai infants during the first 6 months comparing exclusive (EBF), predominant (PBF) and partial (PartBF) breastfeeding

Time frame: 6 months