The Role of Netrin -1 in Acute Coronary Syndrome

Aksaray University Training and Research Hospital238 enrolled

Overview

In our study, Netrin -1; We found that patients with ACS increased at the time of admission, decreased TIMI 3 flow after angiography, and higher risk groups in high risk groups such as TIMI and GRACE were found to have higher Netrin-1 levels.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

SINGLE

Enrollment

238

Conditions

Acute Coronary Syndrome

Interventions

netrin-1 value on admission to hospitalOTHER

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients over the age of 18 * diagnose ACS * patients undergoing angiography Exclusion Criteria: * CVE history * Neurological disease * Pregnancy and Lactation * Liver failure * Diagnosed malignity * Use of anticonvulsant and nephrotoxic medication * Chronic kidney disease * Not having angiography * Developing acute renal failure after angiography * Patients who rejected to participate were excluded.

Outcomes

Primary Outcomes

serum netrin-1 value

Netrin-1 in plasma was measured by enzyme-linked immunosorbent assay (ELISA) (Mybıosource MBS044526 ) All assays were performed in duplicate. Plasma Netrin-1 is expressed in picograms (pg) per mg.

Time frame: 30 minute

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.