Palliative Management of Inoperable Malignant Bowel Obstruction

Inclusion Criteria: * Age ≥ 18 years of age. * Diagnosis of partial bowel obstruction secondary to active or prior malignancy (primary or metastatic GI, GYN, and carcinomatosis) caused either by tumor itself or adhesions inthe setting of active malignancy. * Cross-sectional imaging performed within 24 hours of clinical symptoms of bowel obstruction (nausea, vomiting, and constipation ± abdominal pain) during hospital admission. * Patient must have an inoperable MBO * Participant must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved writteninformed consent form prior to receiving any study related procedure. Exclusion Criteria: * Evidence of complete bowel obstruction by imaging. * Bacteremia/septicemia with a documented positive blood culture: If a blood culture comes back positive after study enrollment, patient will be excluded. * Patients already taking a steroid equivalent to 8 mg of dexamethasone per day prior to study enrollment. * Patients undergoing bowel surgery or stent placement for bowel obstruction. * Those patients with MBO in setting of incarcerated hernia. * Known history of QT prolongation syndrome or if QTc is \> 450 msec in males or \> 470 msec in females on baseline EKG within 2 weeks of enrollment. * Lack of decision making capacity/delirium. * Pregnant or nursing female participants. * Actively suicidal patients. * Acute cholecystitis