The objective of the study is to develop prediction equations for calculating Fat-Free Mass FFM, Total Body Water TBW, Extracellular Water ECW, Visceral Adipose Tissue VAT, total Skeletal Muscle Mass SMM and segmental SMM in a group of elderly. The prediction equations are based on linear regression analysis between the gold standard reference methods Air Displacement Plethysmography ADP, Dual-energy X-ray Absorptiometry DXA, Magnet Resonance Imaging MRI, Deuterium dilution method (D2O) and Sodium Bromide dilution method (NaBr) on the one hand and bioelectrical impedance measurements on the other hand. Multi-frequency bioimpedance is measured for all body segments: right arm, left arm, right leg, left leg, trunk, right body side and left body side using the seca mBCA 515 in standing position and the seca mBCA 525 in standing and lying position.
Study Type
OBSERVATIONAL
Enrollment
150
Institute of Human Nutrition and Food Science
Kiel, Germany
Total Body Water
Total body water (TBW) by deuterium (D2O) dilution
Time frame: 15 minutes
Extracellular Water
Extracellular water (ECW) by NaBr dilution
Time frame: 15 minutes
Fat-free Mass
Fat-free mass by a 4-compartment model based on dual energy x-ray absorption (DXA), air displacement plethysmography (ADP), D2O dilution and weight
Time frame: 15 minutes
Skeletal Muscle Mass
Skeletal muscle mass (SMM) by magnetic resonance imaging (MRI)
Time frame: 1 hour
Visceral Adipose Tissue
Visceral adipose tissue (VAT) by magnetic resonance imaging MRI
Time frame: 1 hour
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