This study aimed to investigate the effects of Game based dual-task training with treadmill on executive function and dual-task performance in individuals with early-onset PD and discuss the correlation between the change values of executive function and dual-task performance after training. Besides, investigate cortical activation after training.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
40
Participants in the experimental group will receive game based dual-task training with a treadmill
Participants in the control group will receive treadmill training
Dual-task walking performance
To evaluate gait parameters while doing dual-task walking
Time frame: Change from baseline at 8 weeks
Single walking performance
To evaluate gait parameters while doing single walking
Time frame: Change from baseline at 8 weeks
Timed up and go test
To evaluate functional walking ability
Time frame: Change from baseline at 8 weeks
Parkinson's Disease Questionnaire 39
To evaluate the quality of life
Time frame: Change from baseline at 8 weeks
Frontal lobe battery test-Chinese version
To evaluate executive function
Time frame: Change from baseline at 8 weeks
Trail-making test
To evaluate executive function
Time frame: Change from baseline at 8 weeks
Stroop color and word test-Chinese version
To evaluate executive function
Time frame: Change from baseline at 8 weeks
Verbal fluency test-Chinese version
To evaluate executive function
Time frame: Change from baseline at 8 weeks
Digit span test
To evaluate executive function
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Time frame: Change from baseline at 8 weeks
Dual-task costs
To compare the cost between doing dual task and single task
Time frame: Change from baseline at 8 weeks
Functional near-infrared spectroscopy
To evaluate the changes of blood perfusion in frontal lobe
Time frame: Change from baseline at 8 weeks