To evaluate the efficacy and safety of Kangfu Xiaoyan Suppository in the treatment of pelvic inflammatory diseases (dampness-heat accumulation syndrome) and its influence on the sequelae of pelvic inflammatory diseases, and to study the role of traditional Chinese medicine in reducing the use of antibiotics and the risk of clinical medication, taking levofloxacin + metronidazole as the control drug.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
240
To evaluate the short-term and long-term efficacy of traditional Chinese medicine of Kangfu anti-inflammatory suppository in reducing the use of antibiotics,reducing the risk of clinical use of drugs.
The MCCormack scale scores of 240 subjects will be assessed
assessment of the 70% reduction rate after treatment
Time frame: Change from base line on the 56 days after discontinuation
The neutrophils of 240 participants will be assessed
assessment of neutrophils returning to normal reference range
Time frame: Change from base line on the 28 days of medication and 56 days after discontinuation
The whole blood reduced viscosity from hemorheological tests of 240 participants will be assessed
assessment of whole blood viscosity returning to normal reference range
Time frame: Change from base line on the 28 days of medication and 56 days after discontinuation
The plasma viscosity from hemorheological tests of 240 participants will be assessed
assessment of the plasma viscosity returning to normal reference range
Time frame: Change from base line on the 28 days of medication and 56 days after discontinuation
The CRP of 240 participants will be assessed
assessment of the CRP returning to normal reference range
Time frame: Change from base line on the 28 days of medication and 56 days after discontinuation
The volume of liquid on B-mode of 240 subjects will be assessed
The changes of the volume of liquid on B-mode at different observation points before and after treatment will be assessed
Time frame: Change from base line on the 28 days of medication and 56 days after discontinuation
The white blood cells of 240 participants will be assessed
assessment of the white blood returning to normal reference range
Time frame: Change from base line on the 28 days of medication and 56 days after discontinuation
The TCM syndrome scores of 240 subjects will be assessed
assessment of the 70% reduction rate after treatment
Time frame: Change from base line on the 56 days after discontinuation
The VAS score of 240 subjects will be assessed
assessment of the 70% reduction rate after treatment
Time frame: Change from base line on the 56 days after discontinuation
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