A Study to Investigate BMS-986256 at steady state and its effect on Mycophenolate Mofetil exposure in Healthy Male Participants
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
PREVENTION
Masking
NONE
Enrollment
15
specified dose on specified days
specified dose on specified days
PRA Health Sciences - Salt Lake
Salt Lake City, Utah, United States
Mycophenolic Acid (MPA) PK parameter: Maximum observed plasma concentration (Cmax)
Time frame: days 1-5 and days 26 -30
mycophenolic acid (MPA) PK parameter: area under the concentration-time curve from time zero to the time of the last quantifiable concentration AUC (0-T)
Time frame: Days 1-5 and Days 26 -30
Mycophenolic Acid (MPA) PK parameter:area under the concentration-time curve from time zero extrapolated to infinite time AUC (INF)
Time frame: Days 1-5 and days 26 -30
Incidence of Adverse Events (AEs)
Time frame: up to 51 days
Incidence of Serious Adverse Events (SAEs)
Time frame: up to 51 days
Number of Clinically significant changes in lab assessment of blood serum
Time frame: up to 51 days
Number of Clinically significant changes in assessment of blood
Time frame: up to 51 days
Number of Clinically significant changes in lab assessment of urine
Time frame: up to 51 days
Vital signs of blood pressure
Time frame: up to 51 days
Vital signs of body temperature
Time frame: up to 51 days
Vital signs of respiratory rate
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Time frame: up to 51 days
Number of Participants with abnormal physical examination findings
Time frame: up to 51 days