Development of the Effectiveness of Rehabilitation Tools for Neurovisual Disorders in Patients With Posterior Cortical Atrophy

Centre Hospitalier Universitaire de Nice3 enrolled

Overview

Posterior cortical atrophy (PCA) is manifested by neuro-visual disorders that alter the spatial location of objects, their manipulation and/or recognition. Its etiology is most often neurodegenerative, with a major impact on the autonomy and mood of patients and their families. Few studies have focused on non-medication management of these disorders. The present study thus has a double objective: the development of a complete tool to work on the recognition, localization and/or manipulation of objects; and the evaluation of the effectiveness of this type of management.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Posterior Cortical Atrophy

Interventions

Recognition of objects

* Name of shapes / colors / images / objects * Classification of shapes / colors / images / objects

Location of objectsBEHAVIORAL

* Search for frequent/rarse targets among distractors sharing one or more characteristics with the target * Hit/catch a stationary/mobile target as quickly as possible

Manipulation of objectsBEHAVIORAL

* Storage of shapes/objects * Use of everyday objects (pen, cutlery, etc.)

Eligibility

Sex: ALLMin age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age \>50 years old * Male or Female * Patients with a diagnosis of PCA according to the criteria of Tang-Wai et al (2004) * MMS\>15 * Voluntary, written and informed consent of the patient himself or its legal representative (guardian/curator), with oral consent of the patient in all cases * Anti-Alzheimer's and psychotropic treatments stable for one month, if taken by the patient * Affiliation to a social security system Exclusion Criteria: * Uncorrected visual disorders with non-degenerative etiology (AV\<0.5) * Person under the protection of justice * Pregnant women (a pregnancy test will be performed in premenopausal women)

Locations (1)

Institut Claude Pompidou - Centre Mémoire de Ressources et de Recherche du CHU de Nice

Nice, Alpes-Maritime, France

Outcomes

Primary Outcomes

Effectiveness evaluation

Effectiveness will be evaluated a score based on success rate (from 0 to 10), reaction time and eye-recording .

Time frame: At week 34

Data from ClinicalTrials.gov

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