The investigator retrospectively analyzed consecutive young (\<60 years) cryptogenic stroke patients with Patient Foramen Ovale (PFO) recruited between January 2016 and May 2019 in our center, and compared these patients with sex- and age-matched controls with cryptogenic stroke without PFO. Analyzed baseline characteristics: sex, age, cardiovascular risk factors, history of stroke, and cortical/subcortical localization, arterial territory, number of lesions, and lesion size of the acute symptomatic infarction, together with the ROPE score. The presence and the number of acute and chronic SCCI lesions were assessed.
Study Type
OBSERVATIONAL
Enrollment
50
MRI was performed with a 1.5T magnet (Ingenia, Philips, The Netherlands; diffusion-weighted imaging b-values = 0 and 1,000 s/mm2, TR 4,280 ms, and TE 97 ms). In case of technical problems with the 1.5T MRI scanner, a 3T magnet (Skyra, Siemens, Erlangen, Germany) was used. MRI was analyzed by an experienced rater (DR), blinded to clinical data and MRI sequences other than diffusion-weighted imaging.
Contrast transoesophageal echocardiography (including Valsalva manoeuvre)
CHU Nîmes
Nîmes, France
number of infarction lesions
Number (increase)
Time frame: day 1
infarction location
anterior, posterior, or mixed anterior-posterior circulation and the cortical/subcortical/corticosubcortical location of infarction
Time frame: day 1
size of subcortical lesion
\< or \>15mm
Time frame: day 1
presence of multiterritorial infarction
mixed anterior-posterior circulation or bilateral anterior circulation
Time frame: day 1
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