Patients with severe CAR-T cell associated cytokine release syndrome (CRS) (defined as vasopressor dependent) will be treated with standard of care (SOC) + cytokine adsorption (6hourly for 24 hrs). Primary endpoint is the change in plasma IL-6 between 0 and 24 hrs.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
34
extracorporeal cytokine adsorption
Hannover Medical School
Hanover, Germany
RECRUITINGUniversitätsspital Zürich (USZ)
Zurich, Switzerland
RECRUITINGIL-6 change
Time frame: 24 hours
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