Perinatal Opioid Use

Medical University of South Carolina98 enrolled

Overview

To compare maternal and newborn outcomes among pregnant women with OUD receiving care via telemedicine versus in-person.

Participants: Pregnant women with OUD. Intervention: Participants were seen weekly for four weeks, every two weeks for four weeks and monthly thereafter and provided relapse-prevention therapy and buprenorphine. Design: A cohort derived from a prospectively collected database including 98 women receiving perinatal OUD treatment in an obstetric practice by telemedicine or in-person and followed until 6-8 weeks postpartum from September, 2017 to December, 2018. Logistic regression with propensity score adjustment was applied to reduce group selection bias and control for potentially confounding variables. Setting: Four outpatient obstetric practices in the southeast.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Opioid Use Pregnancy

Interventions

In-Person Perinatal OUD TreatmentBEHAVIORAL

Participants were seen weekly for four weeks, every two weeks for four weeks and monthly thereafter and provided relapse-prevention therapy and buprenorphine as part of standard of care.

Perinatal OUD Treatment via TelemedicineBEHAVIORAL

Participants were seen weekly for four weeks, every two weeks for four weeks and monthly thereafter and provided relapse-prevention therapy and buprenorphine as part of standard of care..

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 45 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adult females, any race or ethnicity, age 18-45 years * Currently pregnant * Opioid Use Disorder (OUD) * received in person or telemedicine treatment for OUD in their obstetrician's office Exclusion Criteria: * Not currently pregnant or receiving perinatal care * Not in agreement with Patient-Physician Agreement

Locations (1)

The Medical University of South Carolina

Charleston, South Carolina, United States

Outcomes

Primary Outcomes

Number of individuals retained in treatment

Uninterrupted addiction treatment during pregnancy through 6-8 weeks postpartum

Time frame: 6-8 weeks postpartum

Percent of infants born with Neonatal Abstinence Syndrome (NAS)

Newborn withdrawal, also know as NAS gathered via electronic health record

Time frame: At Delivery

Secondary Outcomes

Positive urine drug screens

Number of individuals with a positive urine drug screen

Time frame: At delivery and 6-8 weeks postpartum

Length of newborn hospital stay and birth weight

Average number of days infant was in the hospital following delivery; weight of infant at birth

Time frame: Assessed up to 6 months following delivery

Data from ClinicalTrials.gov

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