Participants will be randomized either to home-based exercise or to intradialysis exercise guided by nurses of the renal unit. The programs will last 16 weeks. The intradialysis exercise consists of combined aerobic and resistance training exercise. The home-based exercise consists of resistance exercise and walking.
During 16 weeks one group will follow an intradialysis exercise program. The exercise program consists of strengthening exercises for lower limbs and for the upper limb free of fistula. The exercise program includes isotonic exercises for quadriceps, triceps surae, psoas, glutei, and brachial biceps; and isometric exercises for hip adductors and hamstrings. Elastic bands will be used to apply resistance. Progression will be achieved by increasing from 1 set of 10 repetitions until 3 sets of 15 repetitions. This first part of the exercise session will last no more than 30 minutes. The program will also include aerobic exercise (cycling) for up to 30 minutes. Intensity will adapted through the duration of the study so that the participant feel the exercise from hard to somewhat hard (13 to 15 at the rate of perceived exertion 6 to 20). Time and resistance will be adapted progressively. After an initial training period by a physiotherapist, the nursing staff will be responsible for monitoring and implementing the program. The other group will follow a home-based program. A booklet with resistance exercise and recommendation of walking between exercises will be provided. An initial training phase will be applied by the physiotherapists from the rehabilitation department.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
70
Combined exercise, aerobic and resistance training, implemented by nursing staff
Combined exercise, aerobic and resistance training, implemented independently home
KU Leuven
Leuven, Belgium
Aristotle University of Thessaloniki
Thessaloniki, Greece
Hospital de Manises
Manises, Valencia, Spain
Universitat de Valencia
Valencia, Spain
Change from baseline short physical performance battery at 16 weeks
Score achieved at the battery that includes balance tests (4 points), sit to stand to sit 5 (4 points) and and gait speed (4 points). The total score is calculated , from 1 to 12, being 12 the highest functional score
Time frame: Baseline, 16 weeks
Change from baseline gait speed at 16 weeks
Speed to cover 4 meters, in meters/second
Time frame: Baseline, 16 weeks
Change from baseline sit to stand 10 test at 16 weeks
Time to perform 10 repetitions sit to stand
Time frame: Baseline, 16 weeks
Change from baseline sit to stand 60 test at 16 weeks
Sit to stand repetitions performed in 60 seconds
Time frame: Baseline, 16 weeks
Change from baseline 6 minutes walk test at 16 weeks
Number of meters walked in 6 minutes
Time frame: Baseline, 16 weeks
Change from baseline handgrip strength at 16 weeks
Bilateral handgrip strength
Time frame: Baseline, 16 weeks
Change from baseline one-leg heel rise test at 16 weeks
Number of heel rise repetitions achieved
Time frame: Baseline, 16 weeks
Change from baseline one-leg standing test at 16 weeks
Time achieved while standing on one leg
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Universiat de Valéncia
Valencia, Spain
Skane Univeristy Hospital
Lund, Sweden
Karolinska Institute
Stockholm, Sweden
Time frame: Baseline, 16 weeks
Change from baseline timed up and go test at 16 weeks
Time to stand up, walk 3 meters, come back and sit down again
Time frame: Baseline, 16 weeks
Change from baseline Physical activity level at 16 weeks
Physical activity questionnaires
Time frame: Baseline, 16 weeks
Change from baseline Health related quality of life at 16 weeks
Medical outcomes survey Short Form 36 questionnaire to measure health-related quality of life, rated from 0 to 100, being the highest score the better the quality of life
Time frame: Baseline, 16 weeks
Adherence, as number of sessions performed /number of sessions offered
Sessions performed/sessions offered
Time frame: 16 weeks