Drug-Drug Interaction Study of TAK-788 and Midazolam in Participants With Advanced Non-small Cell Lung Cancer (NSCLC)

Inclusion Criteria: 1. Histologically or cytologically confirmed locally advanced NSCLC in which the participant is not a candidate for definitive therapy; or, the participant has recurrent or metastatic (Stage IV) disease. 2. Refractory or intolerant to standard available therapies. 3. Eastern Cooperative Oncology Group (ECOG) performance status 0 to 1. 4. Minimum life expectancy of 3 months or more. 5. Adequate organ function as defined by the following criteria: * Total serum bilirubin less than or equal to (\<=) 1.5\*upper limit of normal (ULN) (\<=3\*ULN for participants with Gilbert syndrome or if liver function abnormalities are due to underlying malignancy) * Alanine aminotransferase and aspartate aminotransferase \<=2.5\*ULN (or \<=5\*ULN if liver function abnormalities are due to underlying malignancy) * Estimated creatinine clearance greater than or equal to (\>=) 30 milliliter per minute (mL/min) (calculated by using the Cockcroft-Gault equation) * Serum albumin \>= 2 gram/deciliter (g/dL) * Serum lipase/amylase \<=1.5\*ULN; and * Serum amylase \<=1.5\*ULN unless the increased serum amylase is due to salivary isoenzymes. 6. Adequate bone marrow function as defined by the following criteria: * Absolute neutrophil count \>=1.5\*10\^9 per liter (/L) * Platelet count \>=75\*10\^9/L; and * Hemoglobin \>=9.0 g/dL. 7. Normal QT interval on screening electrocardiogram (ECG), defined as QT interval with Fridericia's correction (QTcF) of \<= 450 millisecond (msec) in males or \<= 470 msec in females. (as conducted and interpreted in accordance to local institutional practices and confirmed by principal investigator \[PI\]). 8. All toxicities from prior anticancer therapy must have resolved to \<= Grade 1 according to the National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) version 5.0 or have resolved to baseline, at the time of first dose of TAK-788. Note: treatment-related Grade 2 or 3 alopecia and treatment-related Grade 2 peripheral neuropathy are allowed if deemed irreversible. 9. Suitable venous access for study-required blood sampling (that is, including for PK, pharmacodynamics, and clinical laboratory tests). Exclusion Criteria: 1. Received a strong or moderate cytochrome P450 3A (CYP3A) inhibitor or strong or moderate CYP3A inducer within 2 weeks prior to the first dose of TAK-788. 2. Received small-molecule anticancer therapy (including but not limited to cytotoxic chemotherapy and investigational agents) within 2 weeks prior to the first dose of TAK-788. 3. Received antineoplastic monoclonal antibodies including check point inhibitors within 28 days of the first dose of TAK-788. 4. Received radiotherapy \<=14 days prior to the first dose of TAK-788. However, participants are allowed to receive any of the following treatments up to 7 days prior to the first dose: (a) Stereotactic radiosurgery (SRS) (b) stereotactic body radiation therapy (SBRT) or (c) palliative radiation outside the chest and brain. 5. Major surgery within 28 days prior to the first dose of TAK-788. Minor surgical procedures, such as catheter placement or minimally invasive biopsy, are allowed. 6. Diagnosed with another primary malignancy other than NSCLC except for adequately treated non-melanoma skin cancer or cervical cancer in situ; definitively treated non-metastatic prostate cancer; or another primary malignancy and is definitively relapse-free with at least 3 years elapsed since the diagnosis of the other primary malignancy. 7. Have known active brain metastases (have either previously untreated intracranial central nervous system (CNS) metastases or previously treated intracranial CNS metastases with radiologically documented new or progressing CNS lesions). Brain metastases are allowed if they have been treated with surgery and/or radiation and have been stable without requiring corticosteroids to control symptoms within 7 days before the first dose of TAK-788, and have no evidence of new or enlarging brain metastases. 8. Current spinal cord compression (symptomatic or asymptomatic and detected by radiographic imaging) or leptomeningeal disease (symptomatic or asymptomatic). 9. Have uncontrolled hypertension. Participants with hypertension should be under treatment on study entry to control blood pressure. 10. Significant, uncontrolled, or active cardiovascular disease, including, but not limited to the following: * Myocardial infarction within 6 months prior to the first dose of study drug; * Unstable angina within 6 months prior to the first dose of study drug; * Congestive heart failure within 6 months prior to the first dose of study drug. Cardiac ejection fraction \<50% by echocardiogram (ECHO) or multiple gated acquisition scan (MUGA); * History of clinically significant (as determined by the treating physician) atrial arrhythmia; * Any history of ventricular arrhythmia; or * Cerebrovascular accident or transient ischemic attack within 6 months prior to the first dose of study drug. 11. Treatment with medications known to be associated with the development of torsades de pointes. 12. Gastrointestinal illness or disorder that could affect oral absorption of TAK-788 or midazolam.