Despite the critical importance of identifying hospital-associated outbreaks as early as possible in order to limit their spread, there are currently no standardized methods for cluster detection. The CLUSTER Trial (Cluster Linkage Using Statistics to Trigger and Evaluate Response) will assess whether a statistically-based automated cluster detection method coupled with a robust response protocol will enable rapid containment of hospital clusters as measured by a reduction in cluster size and duration as compared to routine hospital cluster detection methods coupled with the same response protocol. Note: that enrolled "subjects" represents 82 individual HCA Healthcare hospitals that have been randomized
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
2,905,455
Hospitals will use routine practices for cluster detection with a structured cluster response protocol when a cluster is detected.
Hospitals will use an automated statistical cluster detection tool in addition to routine practices for cluster detection with a structured cluster response protocol when a cluster is detected.
Riverside Community Hospital
Riverside, California, United States
Regional Medical Center of San Jose
San Jose, California, United States
Los Robles Regional Medical Center
Thousand Oaks, California, United States
Swedish Medical Center
Denver, Colorado, United States
Sky Ridge Medical Center
Denver, Colorado, United States
Cluster Size
Cluster size defined as number of cases identified after the initial cluster signal through the last cluster case. NOTE: this outcome is intended for the primary manuscript.
Time frame: 30 months
Cluster Duration
Cluster duration defined as number of days from the initial cluster signal through the last cluster case. NOTE: this outcome is intended for the primary manuscript.
Time frame: 30 months
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Presbyterian St. Luke's Medical Center
Denver, Colorado, United States
Rose Medical Center
Denver, Colorado, United States
North Suburban Medical Center - JV
Thornton, Colorado, United States
JFK Medical Center
Atlantis, Florida, United States
Brandon Regional
Brandon, Florida, United States
...and 72 more locations