Persistent hypoparathyroidism is an underestimate but major complication of total thyroidectomy. The hypothesis of the investigators is that the mental health is impaired in hypoparathyroid patients compared with thyroidectomized patients without hypoparathyroidism. The investigators evaluated the quality of life using the SF-36 survey in comparison with a control population of patients thyroidectomized but free from this complication. The voice quality, the cardiovascular risk, the kidney function and the incidence of urinary lithiasis were also evaluated.
Persistent hypoparathyroidism is an underestimate but major complication of total thyroidectomy. In this retrospective, observational, multicentre study, the investigators evaluated the quality of life using the SF-36 survey in comparison with a control population of patients thyroidectomized but free from this complication. Patients in six centers in France (Angers, Le Mans, Limoges, Nancy, Nantes, la Pitié-Salpétrière) and in the association "Hypoparathyroïdisme France" were contacted by mail. The primary endpoint was the mental health. The physic and global quality of life scores were assessed as secondary endpoints. Medical and VHI surveys were also send to the patients. The voice quality, the cardiovascular risk, the kidney function and the incidence of urinary lithiasis were also evaluated.
Study Type
OBSERVATIONAL
Enrollment
143
Non-interventional study
CHU Angers
Angers, France
Centre Hospitalier Le Mans
Le Mans, France
CHU Limoges
Limoges, France
CHU Nancy
Nancy, France
CHU Nantes
Nantes, France
AP-HP La Pitié Salpétrière
Paris, France
Mental health
Items from mental quality of life score defined by the SF36 (Short Form 36) survey
Time frame: Through study completion, an average of 1 year
Physical quality score
Items from the SF36 (Short Form 36) survey
Time frame: Through study completion, an average of 1 year
Global quality of life score
Items from the SF36 (Short Form 36) survey
Time frame: Through study completion, an average of 1 year
Voice quality
Items from the VHI (Voice Handicap Index) survey
Time frame: Through study completion, an average of 1 year
Renal function quality
Serum creatinine and clearance dosage
Time frame: Through study completion, an average of 1 year
Presence of urinary lithiasis
Serum creatinine and clearance dosage
Time frame: Through study completion, an average of 1 year
Presence of cardiovascular complications
Defined as ischemic cardiopathy
Time frame: Through study completion, an average of 1 year
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