The aim of the current study, therefore, is to determine the feasibility of recruitment and adherence to resistance exercise training interventions performed at low and high loads, to volitional muscular failure, in a trial population that includes both healthy and frail older people.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
60
leg extension, leg press, leg curl and calf press
leg extension, leg press, leg curl and calf press
GRI Clinical Research Facility
Glasgow, United Kingdom
Muscle strength
Knee extensor maximal torque during an isometric MVC
Time frame: Change from baseline to 8 weeks
Vastus lateralis muscle thickness
Measured via ultrasound
Time frame: Change from baseline to 8 weeks
Muscle strength
Knee flexor maximal torque during an isometric MVC
Time frame: Change from baseline to 8 weeks
One-repetition maximum
leg extension, leg curl, leg press and calf press
Time frame: Change from baseline to 8 weeks
Biomechanics during walking and stair climbing
Motion analysis
Time frame: Change from baseline to 8 weeks
Short performance physical battery test
SPPB - balance, walking pace and chair rise
Time frame: Change from baseline to 8 weeks
Quality of life measure
EQ-5D-5L questionnaire
Time frame: Change from baseline to 8 weeks
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.