Study of the Imaging Agent 18F-Var3 in Patients With Breast Cancer

Inclusion Criteria: * Age 18 years or greater * Biopsy-proven breast malignancy * \>/= 1 viable lesion, \>/= 1 cm, confirmed on CT, MR, or FDG PET/CT within 4 weeks of protocol enrollment * Newly diagnosed or recurrent disease, on or off therapy * ECOG performance of 0-2 \*Note: Lesions are considered viable if they are stable or increasing soft tissue lesions, or if they are FDG-avid bone lesions Exclusion Criteria: * Life expectancy \< 3 months * Pregnancy or lactation * Biopsy or other surgical procedures within 48 hours prior to receiving study intervention * Patients who cannot undergo PT/CT scanning because of weight limits. PET/CT scanners may not be able to function with patients over 400 pounds