PTSD is characterized by physiological changes, some of which are thought to be chronic, while others are observed in response to stressogenic stimuli. Prolonged Exposure (PE) therapy is a widely used protocol considered highly affective among individuals diagnosed with PTSD. The current study is a non-interventional observational study, aimed at measuring changes in the digital phenotype of participants with PTSD during and following PE therapy. Physiological data will be collected using wearable sensors during the sessions, and participants will be assessed using questionnaires and psychiatric assessments before and after the completion of their imaginal or writing based PE therapy (10-15 sessions).
Study Type
OBSERVATIONAL
Enrollment
100
Changes in Heart Rate
Heart Rate and HRV (Heart Rate Variability)
Time frame: 3 months
Changes in Saturation
Changes in saturation SPO2 (oxygen saturation by pulse oximetry)
Time frame: 3 months
Changes in blood pressure
Changes in Continuous Blood Pressure
Time frame: 3 months
Changes in Pulse Pressure
Changes in Pulse Pressure
Time frame: 3 months
Changes in Respiratory rate
Changes in Respiratory rate
Time frame: 3 months
Changes in Stroke Volume
Changes in Stroke Volume
Time frame: 3 months
Changes in Systemic Vascular Resistance
Changes in Systemic Vascular Resistance
Time frame: 3 months
Changes in sweat
Changes in Sweat
Time frame: 3 months
Changes in Body Temperature
Changes in Body Temperature
Time frame: 3 months
Changes in Cardiac Output
Changes in Cardiac Output
Time frame: 3 months
Correlation between changes in digital phenotype (multiple measures)
Correlation between changes in digital phenotype during the sessions and the clinical improvement according to the psychiatric evaluation and questionnaires.
Time frame: 3 months
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