GLS-1200 Topical Nasal Spray to Prevent Sinusitis After Endoscopic Sinus Surgery

Inclusion Criteria: * Age 18 years or older; * Able to provide informed consent * Able and willing to comply with study procedures * Elective FESS * Able and willing to utilize an approved form of pregnancy prevention for women of child bearing potential Exclusion Criteria: * Pregnancy or documentation of pregnancy by pre-operative pregnancy test * History of primary ciliary dyskinesia * Known allergy to quinine, quinidine or mefloquine * Know latex allergy * History of hematologic malignancy * History of bone marrow transplantation * Current or planned chemotherapy treatment for hematologic or solid tumor during study period * FESS performed non-electively and /or in preparation for decontamination of the sinuses related to cystic fibrosis or in preparation for chemotherapy, solid organ transplantation, or bone marrow transplantation