To evaluate the safety and efficacy of treatment of children with acute bacterial infection disease with Ceftriaxone Sodium and Sulbactam Sodium for Injection in the condition of widely used, and provide the basis of adjusting the dosage regimen for children in particular.
Ceftriaxone sodium and sulbactam sodium for injection (2:1)plays a therapeutic role by the former inhibiting bacterial cell wall synthesis,the latter making irreversible competitive inhibition of β-lactamase.The antimicrobial effect of Ceftriaxone can be enhanced by the two combined. The compound specifically aims to the mechanism of bacterial resistance, extending the life of Ceftriaxone in the treatment-resistant pathogen infections.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
30
daily dose was 75 mg/kg by weight, 1-2 times ivgtt per day, 4 to 14 days
The cure rate of patients
Clinically effective/Clinically ineffective
Time frame: Seven days after treatment
bacterial clearance rate
end of treatment of bacteriological efficacy (bacterial clearance rate)
Time frame: 48 hours after treatment
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