LUEbeck Registry of Intensive Care Patients - Characterization of the Patients Intestinal MICROBIOME

University of Luebeck200 enrolled

Overview

The purpose of the current study is to analyze the effects of ICU-care on changes in microbiome and the influence of intestinal microbiome changes on short-term and long-term morbidity and mortality of ICU patients.

Study Type

OBSERVATIONAL

Enrollment

200

Conditions

ICU Patients

Interventions

Analyze changes in intestinal microbiomeOTHER

Descriptive Analysis

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age ≥18 years * All patients receiving intensive medical care * A written informed consent from the patient or two independent doctors or legal guardians. Exclusion Criteria: * Age \<18 years

Locations (1)

Medical Clinic II-UKSH Campus Lübeck

Lübeck, Schleswig-Holstein, Germany

RECRUITING

Outcomes

Primary Outcomes

Modification of the microbiome

The modification of the microbiome using ribosomal 16 S DNA sequencing and clustering for Operational Taxonomic Units (OTU) and calculated Shannon Index

Time frame: Day 0

Secondary Outcomes

ICU intensive care unit stay

Duration

Time frame: Day 0

Hospital stay

Duration

Time frame: Month 12

Hospital stay

Duration

Time frame: Month 6

Survival

To discharge

Time frame: Month 6

Survival

To discharge

Time frame: Month 12

Central Contacts

Tobias Graf, MD

CONTACT

+49 451 500 75306 tobias.graf@uksh.de

Roza Meyer-Saraei, PhD

CONTACT

+49 451 500 44542 roza.meyer-saraei@uksh.de

Data from ClinicalTrials.gov

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