The purpose of this study is to assess the safety, tolerability, kinetics and test-retest repeatability of the novel LPA1 positron emission tomography (PET) ligand 18F-BMS-986327 in healthy participants and participants with idiopathic pulmonary fibrosis (IPF).
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
14
Imaging Agent
Local Institution - 0001
New Haven, Connecticut, United States
Incidence of adverse events (AEs)
Time frame: Up to 3 days after participant's participation
Incidence of serious adverse events (SAEs)
Time frame: Up to 30 days after participant's participation
Radiation dosimetry calculated from positron emission tomography-computed tomography (PET-CT) images
Time frame: 30 days after participant's participation
Test-retest repeatability
Time frame: 30 days after participant's participation
Biodistribution and lung uptake calculated from PET-CT images in participants with IPF
Time frame: 30 days after participant's participation
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