Observation of Blood Orphanin and Norepinephrine Levels in Diabetic Patients Under Subarachnoid Anesthesia

Second Hospital of Shanxi Medical University120 enrolled

Overview

This study aims to investigate the Influence of Intraspinal anesthesia to the concentrations of blood orphanin, norepinephrine in patients with diabetes mellitus. We hope to explain the relationship between sensory and sympathetic nerves in diabetic patients undergoing intraspinal anesthesia.

Study Type

OBSERVATIONAL

Enrollment

120

Conditions

Intraspinal Anesthesia

Interventions

ELISADIAGNOSTIC_TEST

Detection of blood orphanin and norepinephrine in patients

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients undergoing lower limb surgery under spinal anesthesia Exclusion Criteria: * Emergency surgery * The operation time is more than 3 hours * Combined general anesthesia or nerve block anesthesia

Locations (1)

Second of Shanxi Medical University

Taiyuan, Shanxi, China

Outcomes

Primary Outcomes

Blood orphanin concentration

Concentration of blood orphanin in patients before and after anesthesia

Time frame: 24 hours

Blood norepinephrine concentration

Concentration of blood norepinephrine in patients before and after anesthesia

Time frame: 24 hours

Data from ClinicalTrials.gov

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