Microbial Composition of Breast Milk Collected From Healthy Turkish Women

Hacettepe University20 enrolled

Overview

Breast milk is an optimal source of nutrients for newborns as well as a potential source of bacteria for the intestinal microbiota. However, there are limited number of studies evaluating the relationship between maternal nutrition, breast milk and neonatal intestinal microbiota.

The study was conducted on a total of 20 healthy women following at Obstetrics and Gynecology Department of Gülhane Education and Research Hospital in Ankara Health Sciences University. Sociodemographic characteristics, anthropometric measurements, breastfeeding characteristics were evaluated in the third trimester of the women who underwent routine prenatal care. Breast milk samples were obtained at 16.day postpartum during lactation.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Microbial Community in Breast Milk

Eligibility

Sex: FEMALEMin age: 20 YearsMax age: 31 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Singleton pregnancy * Age 19-35 years * At weeks of 30-36 gestation * No history of acute or chronic diseases * Term delivery Exclusion Criteria: * Alcohol use * Smoking * Gestational diabetes * Type 1 and 2 diabetes * Preeclampsia * Polycystic ovary * Syndrome * Thyroid and parathyroid disease * Metabolic bone or kidney disease * Abnormal liver function * Multiple pregnancy * Premature and postmature labor * Having chemotherapy * Taking drugs such as antibiotics and probiotics

Locations (1)

Hacettepe University

Ankara, Turkey (Türkiye)

Outcomes

Primary Outcomes

Microbial abundance and diversity

The microbial composition of the breast milk samples was determined by 16S rRNA (ribosomal ribonucleic acid) gene sequencing analysis.

Time frame: at 16 day postpartum

Data from ClinicalTrials.gov

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