This is a prospective comparative non-randomized cohort study to understand the long-term vision outcomes, safety, and stability of anterior chamber intraocular lenses (AC IOLs) vs. scleral-fixated intraocular lenses (SF IOLs).
On the pre-operative visit, specular microscopy, biometry, applanation tonometry and ocular coherence tomography (OCT) will be performed. The patient will then undergo treatment as per surgeon's discussion/ decision with the patient for implantation of an AC-IOL or SF-IOL. Participation in the study will not impact the management plan in any way. Specular microscopy will be performed wit the CellChek XL (Konan Medical, Irvine, CA). Biometry will be performed with the IOLMASTER (Carl Ziess Meditec, Jena, Germany), and anterior segment and macular OCT will be performed with the Cirrus-HD OCT (Carl Zeiss Metidec, Jena, Germany). EC count, OCT (macula and anterior segment) and specular microscopy will be performed at baseline, week 1, month 1, month 6, 12 and 24.
Study Type
OBSERVATIONAL
Enrollment
60
Implantation of an intraocular lens using either an anterior chamber IOL or a scleral fixated IOL using the modified Yamane technique.
Sunnybrook Hospital
Toronto, Ontario, Canada
RECRUITINGEndothelial cell loss
Change in endothelial cell count from baseline compared to 24 months post-operatively.
Time frame: Pre-operative (baseline) and 24 weeks post-operatively.
Corrected distance visual acuity (CDVA)
CDVA will be measured using a standardized Early Treatment Diabetic Retinopathy Study (ETDRS) chart
Time frame: Pre-operative (baseline), week 1, months 1, 6, 12 and 24 post-operatively.
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