Computer Aided Detection, Tandem Colonoscopy Study

Inclusion Criteria: * Patients presenting to the endoscopy unit for a screening colonoscopy or a surveillance colonoscopy * Willingness to undergo tandem colonscopies with and without the use of computer-aided software while undergoing conventional colonoscopy with sedation * Ability to provide written, informed consent (approved by IRB) and understand the responsibilities of trial participation Exclusion Criteria: * People with diminished cognitive capacity * Patients undergoing diagnostic colonoscopy (e.g. as an evaluation for active GI bleed) * Patients with incomplete colonoscopies (those where endoscopists did not successfully intubate the cecum due to technical difficulties or poor bowel preparation) * Patients that have standard contraindications to colonoscopy in general (e.g. documented acute diverticulitis, fulminant colitis and known or suspected perforation). * Patients with inflammatory bowel disease * Patients referred for endoscopic mucosal resection (EMR)