Home-based HIIT to Improve CRC Survivorship: Feasibility and Relationship With Novel Surrogate Biomarkers of CRC Recurrence

Inclusion Criteria: 1. Patients who are no more than five years post resection and/or adjuvant therapy for stage II-III Colorectal cancer (CRC). 2. Age 19-75 years old. 3. Engaging in less than 90 minutes per week of structured moderate- or vigorous-intensity aerobic exercise in the past three months 4. No known cardiovascular, metabolic or renal disease, and no signs/symptoms suggestive of cardiovascular, metabolic, or renal disease. 5. Must be able to read, speak and understand English 6. Willing to complete two assessment sessions (at baseline and 12 weeks). 7. Willing to engage in moderate- or vigorous-intensity aerobic exercise at home and use mobile health technology to track exercise adherence to the exercise prescription. 8. Able to provide informed consent and willing to sign an approved consent form that conforms to federal and institutional guidelines. 9. Have regular access to a smart phone and willing to download a free application for device tracking Exclusion Criteria: 1. Functional limitations requiring a walker, scooter, or wheelchair. 2. Clinically evident recurrent disease. 3. Resting blood pressure ≥140/90 at the time of baseline testing. 4. No access to smart phone and/or not willing download the device app