Biological Determinants of Sputum Rheology in Chronic Airway Diseases

Inclusion Criteria: * Affiliate with or beneficiary of the French national single-payer health insurance system * Patient capable of spontaneous mucus expectoration * Consulting or hospitalized at the study centre Inclusion Criteria for the Asthma Group * Never- or former-smoker (\<10 pack-years) * Medical history compatible with asthma * Reversible post-brochodilator (or post-corticosteroid test) ventilatory obstruction (ratio of forced expiratory volume in 1 second : forced vital capacity \< 70%) or significant variation in respiratory function -- OR -- Bronchial hyperresponsiveness demonstrated during a broncho-provocation test Inclusion Criteria for the COPD Group * Current- or former-smokers (\>10 pack years) * Chronic obstructive pulmonary disease according to GOLD criteria Inclusion Criteria for the Bronchiectasis Group * Presence of bronchiectasis on computed tomography scan * Cystic fibrosis has been ruled out Exclusion Criteria: * Patient expresses opposition to the protocol * Breast feeding or pregnant * Metastatic neoplastic disease * Other active pulmonary disease (tuberculosis, interstitial lung disease) * Recent psychiatric disorder (in the past year and documented via a specialist consult) * Consumption of illicit drugs or alcoholism * Patients in an exclusion period determined by another study * Patients under any type of legal guardianship * Prisoners * Impossible to correctly inform the patient * Does not fluently read French * Emergency situations