Acute Kidney Injury in Adult Patients Supported by VA-ECMO

Groupe Hospitalier Pitie-Salpetriere347 enrolled

Overview

Post-cardiotomy cardiogenic shock (PCCS) occurs in 2-6% of patients undergoing cardiac surgery, and 1% of cardiac surgery patients will require mechanical circulatory support using Veno-Arterial ExtraCorporeal Membrane Oxygenation (VA-ECMO). Acute Kidney Injury is a frequent complication in this population and negatively impacts the survival. We aimed to determine whether the timing of ECMO implantation influence the renal prognosis of these patients.

Study Type

OBSERVATIONAL

Enrollment

347

Conditions

Acute Kidney Injury Cardiogenic Shock

Interventions

No interventionOTHER

No intervention

Eligibility

Sex: ALLMin age: 18 YearsMax age: 99 Years

Medical Language ↔ Plain English

Inclusion Criteria: * All patients admitted in post-operative of cardiac surgery * Assisted by VA-ECMO Exclusion Criteria: * Chronic hemodialysis * Death occurring within the first 48 hours of VA-ECMO implantation * Multiple VA-ECMO during the same hospitalization.

Locations (1)

Dr Adrien Bouglé

Paris, France

Outcomes

Primary Outcomes

Occurrence of a stage 3 AKI

Number of Participants with Stage 3 Acute Kidney Injury according to the Kidney Disease: Improving Global Outcomes (KDIGO) group

Time frame: Day 10 after ECMO implantation

Secondary Outcomes

Mortality at Day 30

Number of Deceased Participants

Time frame: Day 30 after ECMO implantation

Mortality at 6 months

Number of Deceased Participants

Time frame: 6 months after ECMO implantation

Data from ClinicalTrials.gov

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