Assessment of the lung hyperinflation by bodypletysmography in patients with obstructive sleep apnoea treated with continuous positive airway pressure therapy.
Rationale: Obstructive sleep apnoea (OSA) is characterized by repetitive closure of upper airways leading to apnoea (complete airflow cessation) or hypopnoea (airflow limitation \> 50% + blood oxygen desaturation \> 3% or airflow limitation \> 30% blood oxygen desaturation \> 4%). The prevalence of lung hyperinflations in sleep apnoea patients and effect of continuous positive airway pressure (CPAP) therapy is not known. Process: Subjects included in the study will be obstructive sleep apnoea (OSA) patients diagnosed by respiratory polysomnography performed in the Sleep Laboratory, Department of Respiratory Medicine, University Hospital Olomouc. Bodypletysmography will be performed in the time of OSA diagnosis and after 3 months of CPAP therapy. Data will be statistically evaluated after completion of the target number of subjects.
Study Type
OBSERVATIONAL
Enrollment
50
Standard treatment with continuous positive airway pressure
University Hospital Olomouc
Olomouc, Czechia
Change of Vital Capacity (VC) (ml)
Percentage change of Vital Capacity after 3 months of CPAP therapy.
Time frame: 3 months
Change of Forced Expiratory Volume in 1 second (FEV1) (ml)
Percentage change of Forced Expiratory Volume in 1 second after 3 months of CPAP therapy.
Time frame: 3 months
Change of Total Lung Capacity (TLC) (ml)
Percentage change of Total Lung Capacity after 3 months of CPAP therapy.
Time frame: 3 months
Change of Residual Volume (RV) (ml)
Percentage change of Residual Volume after 3 months of CPAP therapy.
Time frame: 3 months
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