Craniosynostosis is a rare disorder characterized by a premature fusion of one or more sutures of the skull. Craniosynostosis is usually diagnosed in the first years of life. Several complications may be identified if untreated, notably, developmental delay, and vision problems. In some patients with craniosynostosis a decrease in cerebral blood perfusion can be identified. It might be related to the constriction of the brain caused by premature sutural fusion or the localized constriction of venous sinuses. In this study the investigator use the NIRS which is defined as a non-invasive technique to monitor hemodynamic parameters and hemoglobin oxygen saturation of the brain during the surgical correction of the craniosynostosis. By applying this method the investigator will be able to analyse the changes in cerebral hemoglobin oxygen saturation related to the modification of the skull. Determining changes in brain oxygen saturation by using NIRS before, during and after surgery will help both to better understanding the impact of surgical decompression on improving cerebral oxygenation and to better adapt anaesthesia strategies during surgery.
Study Type
OBSERVATIONAL
Enrollment
40
Regional cerebral oxygen saturation (rScO₂) will be collected by NIRS monitoring before anesthesia induction, during surgery and after extubation, in children with craniosynostosis.
Hospices Civils de Lyon service neurochirurgie pédiatrique
Bron, France
Regional cerebral oxygen saturation measure
Variations of rScO₂ (%, frequency of desaturations) measured by NIRS captors
Time frame: Day 0 before anesthesia
Regional cerebral oxygen saturation measure
Variations of rScO₂ (%, frequency of desaturations) measured by NIRS captors
Time frame: Day 0 during surgery
Regional cerebral oxygen saturation measure
Variations of rScO₂ (%, frequency of desaturations) measured by NIRS captors
Time frame: Day 0 after extubation
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