At present, there are few studies on the clinical remission rate of diabetes after one year discontinuation of oral hypoglycemic drugs after intensive treatment. HMS5552 is a kind of GKA hypoglycemic drug. This study intends to observe the clinical remission rate of diabetes mellitus, beta cell function and blood sugar fluctuation of patients with type 2 diabetes mellitus who have been treated with HMS5552 for 52W or 28W and whose glucose control is up to the standard.
Study Type
OBSERVATIONAL
Enrollment
24
To observe the progress of diabetes mellitus after 52 or 28 weeks of HMS5552 treatment for type 2 diabetes mellitus
Nanjing First hospital
Nanjing, Jiangsu, China
HbA1c
Changes of HbA1c
Time frame: 4 weeks
Fasting glucose
Changes of fasting glucose
Time frame: 4 weeks
Postprandial glucose
Changes of postprandial glucose
Time frame: 4 weeks
C peptide
Changes of C peptide
Time frame: 4-8 weeks
TNF-α
Changes of TNF-α
Time frame: 52 weeks
IL-6
Changes of IL-6
Time frame: 52 weeks
8-iso PGF2α
Changes of 8-iso PGF2α
Time frame: 52 weeks
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