This is a single-center, prospective, double-blind, randomized, vehicle-controlled study to evaluate the efficacy, safety and patient satisfaction of tretinoin 0.05% lotion (Altreno) for chest rejuvenation.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
40
Altreno topical lotion
Lotion not containing active ingredient (tretinoin)
Cosmetic Laser Dermatology/West Dermatology Research Center
San Diego, California, United States
Skin Quality
Nine-point scale to assess skin quality for the appearance of crepiness, coarse lines/wrinkles, skin texture, and skin tone evenness
Time frame: Baseline through Month 6
Investigator Assessment-Fabi-Bolton Wrinkle Scale (FBWS)
Fabi-Bolton Wrinkle Scale (FBWS)
Time frame: Baseline through Month 6
Investigator Assessment-Investigator Percent Improvement Evaluation
Investigator Percent Improvement Evaluation
Time frame: 1, 3, and 6 months
Investigator Assessment-Investigator Global aesthetic improvement scale (I-GAIS)
Investigator Global aesthetic improvement scale (I-GAIS)
Time frame: 1, 3, and 6 months
Subject Assessments-Subject Global aesthetic improvement scale (S-GAIS)
Subject Global aesthetic improvement scale (S-GAIS)
Time frame: 1, 3, and 6 months
Subject Assessments-Patient satisfaction score
Patient satisfaction score
Time frame: 1, 3, and 6 months
Subject Assessments-End of study patient questionnaire
End of study patient questionnaire
Time frame: Month 6
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