Study of NPO-13 During Colonoscopy

Inclusion Criteria: 1. Patients who are between 20 and 85 years at the time of consent 2. Patients who need colonoscopy Exclusion Criteria: 1. Patients with a history of abdominal surgical treatment (including the laparoscopic surgery) including the gynecology operation 2. Patients with contraindication to colonoscopy including the paralytic ileus 3. Patients with a history of shock or hypersensitivity to l-menthol or peppermint oil (mint oil) 4. Patient with contraindication to bowel cleansing preparation 5. Patient with contraindication to pain medicine and sedative medicine 6. Patient with contraindication to butylscopolamine bromide and glucagon 7. Patients on cancer treatment (chemotherapy or radiotherapy) 8. Patient with active inflammatory bowel disease or infectious enteritis 9. Patients who need sedative in colonoscopy 10. Patients who receives a therapeutic colonoscopy 11. Pregnant or lactating women, women of childbearing potential, or women who plan to become pregnant during the study 12. Patients who have received other investigational drugs within four months before consent or who are participating in other clinical studies 13. Patients otherwise ineligible for participation in the study in the investigator's or coinvestigator's opinion