This retrospective and prospective study is to investigate the incidence of Carbapenemase-producing bacteria (CPB) at the University Hospital Basel, the time to detection of CPB and to initiation of infection control measures, the risk factors associated with carriage of CPB, type and duration of previously administrated antibiotic medication, antibiotic treatment, as well as to assess the outcomes of the affected patients.
Study Type
OBSERVATIONAL
Enrollment
100
data collection for demographic data (age, gender, hospital admission and discharge date, length of stay, hospitalization prior to current hospital stay (acute care facilities, long-term healthcare centres, nursing homes), discharge destination, outcome, cause of death, travel history, previous exposure to antibiotics and proton pump Inhibitors)
data collection for clinical data (comorbidities, Charlson Comorbidity Index, immunosuppressive treatment, date of diagnosis of CPB, days between hospital admission and diagnosis of CPB, type of consecutive infection, indwelling vascular hardware, urinary catheterization, surgical therapies)
Division of Infectious Diseases and Hospital Epidemiology
Basel, Switzerland
RECRUITINGincidence of CPB at the University Hospital Basel (number)
incidence of CPB at the University Hospital Basel (number)
Time frame: from January 1st , 2008 until December 31st, 2028
time to detection of CPB (days)
time to detection of CPB (days)
Time frame: from January 1st , 2008 until December 31st, 2028
time to initiation of infection control measures
time to initiation of infection control measures
Time frame: from January 1st , 2008 until December 31st, 2028
time to adequate treatment in patients with CPB infections
time to adequate treatment in patients with CPB infections
Time frame: from January 1st , 2008 until December 31st, 2028
presence of established risk factors for CPB
presence of established risk factors for CPB
Time frame: from January 1st , 2008 until December 31st, 2028
length of hospital stay (days)
length of hospital stay (days)
Time frame: from January 1st , 2008 until December 31st, 2028
discharge destination
discharge destination
Time frame: from January 1st , 2008 until December 31st, 2028
cure from infection
cure from infection
Time frame: from January 1st , 2008 until December 31st, 2028
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
data collection for treatment data (antibiotic therapy, immunosuppressive therapy, concomitant medication)
data collection for microbiological data (species of CPB, type of sample, date of sample, history of colonization or infection with any antibiotic resistant pathogen)
cause-specific mortality (number)
cause-specific mortality (number)
Time frame: from January 1st , 2008 until December 31st, 2028
all-cause mortality (number)
all-cause mortality (number)
Time frame: from January 1st , 2008 until December 31st, 2028