The study evaluates the effect of exercise and/or diet during on body weight, body composition and health related blood parameters. Participants are overweight sedentary females, allocated to four different groups: Normal diet, Low-carb-high-fat diet, Normal diet + exercise, Low-carb-high-fat diet + exercise.
Diet and exercise can both be efficient tools to reduce bodyweight, get healthier body composition and improve many different health related blood parameters such as cholesterol and glucose tolerance. Exercise has superior effect on skeletal muscle in the context of glucose tolerance, but adherence to exercise program can be a huge challenge for overweight individuals. While exercise has profound effect on metabolic health, diet has been superior when it comes to weight reduction. Previous studies have shown that 5-7% weight loss can improve glucose tolerance, measured as reduced fasting glucose and reduced 2-hour post prandial glucose. We wish to see if the combination exercise and diet is superior to diet only when it comes to over all health.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
57
Exercise program - indoor bicycle interval exercise, duration 60 min 3x week
Normal diet recommended by the health authorities
LCHF Diet, a modified Atkins diet with high percentage of fat and very low percentage of karbohydrates
Norwegian School of Sports Sciences
Oslo, Norway
Area under curve (AUC) glucose
AUC glucose measured during an OGTT
Time frame: Change from baseline AUC glucose at 10 weeks
Lipid profile
Measurements of total cholesterol, LDL, HDL, TG
Time frame: Change from Baseline lipids at 10 weeks
Body composition
Measurement of lean body mass, fat free mass, fat mass, visceral fat, bone mass
Time frame: Change from baseline values at 10 weeks
Cardiorespiratory fitness
Measurement of peak oxygen uptake
Time frame: Change from baseline values at 10 weeks
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