The Use of PRP and BMC in Patients With Internal Disc Disruption Multicenter Prospective Randomized Controlled Trial in Patients With Internal Disc Disruption

Inclusion Criteria: * A high index of suspicion for discogenic pain, i.e. painful degenerative discs with or without contained protrusions * Age greater than 18 and less than 70 years * Maintained intervertebral disc heights of at least 50% * Pain not generated from facet joints, sacro-iliac joints or any pathology other than discogenic origin. * Pain is not responsive to conservative treatment measures (oral medications, epidural steroid injections, physical therapy) * Pain persists for an extended period of time (i.e., at least 3 months) * High intensity zone (HIZ) in annular fissure detected on T2 or STIR MRI, degenerated discs or contained disc protrusions. * No evidence of contraindications to undergo procedure such as pregnancy, active infection, bleeding disorder, or metastatic cancer * English speaking Exclusion Criteria: * Disc extrusions, disc sequestrations, severe spinal stenosis, or severe disc degeneration with grade 5 Pfirmann index or with Modic 3 level change. * Patient refusal * Presence of a known bleeding disorder * Pregnancy * Systemic or local infection * Presence of an unstable medical or psychiatric condition * Prior intradiscal procedure (ie. IDET, Nucleoplasty) * Inaccessibility to discs such as fusion * Non-English speaking * Prior fusion surgery