Cognitive, Psychological and Electrophysiological Attributes to Suicide Among Depressed Patients

Mansoura University50 enrolled

Overview

This study will try to provide a better understanding of the psychological, cognitive and electrophysiological factors that contribute to suicide in depressed patients.

Objectives: 1. To investigate the ability of qEEG to suspect suicidal potential in patients diagnosed with major depression. 2. To test the ability of some psychological and cognitive elements in determining the likelihood of suicide in such patients. 3. To give an objective and more reliable method than traditional questionnaires to assess the seriousness of suicidal ideations in patients suffering from depression who usually don't reveal their actual intentions.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Suicide Major Depressive Disorder Quantitative EEG (qEEG)

Interventions

Quantitative EEGDIAGNOSTIC_TEST

1. Both groups will undergo evaluation of depression severity using Beck Depression Inventory Scale-II (Arabic Version) 2. Both groups will be assessed for psychological \& cognitive contributes respectively using: A. Connor and Davidson Scale for resilience (Arabic Version) B. The scale of Islamic Religiosity Attitude (SIRA) 3. Both groups will do Quantitative EEG (qEEG) to detect electrical, functional and brain mapping changes {Using Neurovirtual BW III, Florida, USA) 4. The quantitative analysis of EEG will focus on the following functions: Histogram, Topography, Spectrum Analysis, Spectral Differences, Propagation, Positional Diagram, Medium Amplitude, Ranges of Absolute Frequencies, Ranges of Relative Frequencies, CSA, Spectrum, and CSA Compressed.

Eligibility

Sex: ALLMin age: 16 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Age between 16 and 65 years * Both males and females will be enrolled * Patients present with the clinical picture of Major depression according to DSM 5 criteria. Exclusion Criteria: * Psychotic features associating depressive episode * Bipolar depression * The condition is due to another medical condition * The condition is substance or medication-induced * Intellectual disability * Comorbid epilepsy

Locations (1)

Mansoura University Hospital

Al Mansurah, Dakahlia Governorate, Egypt

RECRUITING

Outcomes

Primary Outcomes

Electrophysiological attibutes to suicide among depressed patients

Quantitative Analysis of EEG tracing from depressed patients experiencing suicidal Ideations

Time frame: 5 months

Data from ClinicalTrials.gov

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