The purpose of this study is to refit habitual wearers of daily disposable contact lenses who currently experience symptoms of dry eye and discomfort during lens wear with a different type of daily disposable contact lens. Ocular signs and symptoms of dry eye will be assessed following the guidelines outlined by the Tear Film and Ocular Surface Society (TFOS) in the Dry Eye Workshop II (DEWS II). The performance of the habitual contact lenses and the study lenses will be determined using different optometric assessments. Study lenses will be worn for one month following a daily disposable wear schedule.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
40
Participants wear delafilcon A contact lenses on a daily disposable basis.
Centre for Ocular Research & Education
Waterloo, Ontario, Canada
Subjective Comfort at End of Day With Contact Lens Wear
Participants rate their end of day comfort on a scale from 0 (worst) to 100 (best).
Time frame: Day 1 after screening with habitual lenses
Subjective Comfort at End of Day With Contact Lens Wear
Participants rate their end of day comfort on a scale from 0 (worst) to 100 (best).
Time frame: Day 3 after screening with habitual lenses
Subjective Comfort at End of Day With Contact Lens Wear
Participants rate their end of day comfort on a scale from 0 (worst) to 100 (best).
Time frame: Day 5 after screening with habitual lenses
Subjective Comfort at End of Day With Contact Lens Wear
Participants rate their end of day comfort on a scale from 0 (worst) to 100 (best).
Time frame: 1-week follow up with habitual lens
Subjective Comfort at End of Day With Contact Lens Wear
Participants rate their end of day comfort on a scale from 0 (worst) to 100 (best).
Time frame: Day 1 after dispense with delefilcon A
Subjective Comfort at End of Day With Contact Lens Wear
Participants rate their end of day comfort on a scale from 0 (worst) to 100 (best).
Time frame: Day 3 after dispense with delefilcon A
Subjective Comfort at End of Day With Contact Lens Wear
Participants rate their end of day comfort on a scale from 0 (worst) to 100 (best).
Time frame: Day 5 after dispense with delefilcon A
Subjective Comfort at End of Day With Contact Lens Wear
Participants rate their end of day comfort on a scale from 0 (worst) to 100 (best).
Time frame: Day 7 after dispense with delefilcon A
Subjective Comfort at End of Day With Contact Lens Wear
Participants rate their end of day comfort on a scale from 0 (worst) to 100 (best).
Time frame: Day 21 after dispense with delefilcon A
Subjective Comfort at End of Day With Contact Lens Wear
Participants rate their end of day comfort on a scale from 0 (worst) to 100 (best).
Time frame: Day 28 after dispense with delefilcon A
Subjective Comfort at End of Day With Contact Lens Wear
Participants rate their end of day comfort on a scale from 0 (worst) to 100 (best).
Time frame: 1-month follow up with delefilcon A
Subjective Rating of End of Day Dryness With Contact Lens Wear
Participants rate their end of day dryness on a scale from 0 (worst) to 100 (best).
Time frame: Day 1 after screening with habitual lenses
Subjective Rating of End of Day Dryness With Contact Lens Wear
Participants rate their end of day dryness on a scale from 0 (worst) to 100 (best).
Time frame: Day 3 after screening with habitual lenses
Subjective Rating of End of Day Dryness With Contact Lens Wear
Participants rate their end of day dryness on a scale from 0 (worst) to 100 (best).
Time frame: Day 5 after screening with habitual lenses
Subjective Rating of End of Day Dryness With Contact Lens Wear
Participants rate their end of day dryness on a scale from 0 (worst) to 100 (best).
Time frame: 1-week follow up with habitual lens
Subjective Rating of End of Day Dryness With Contact Lens Wear
Participants rate their end of day dryness on a scale from 0 (worst) to 100 (best).
Time frame: Day 1 after dispense with delefilcon A
Subjective Rating of End of Day Dryness With Contact Lens Wear
Participants rate their end of day dryness on a scale from 0 (worst) to 100 (best).
Time frame: Day 3 after dispense with delefilcon A
Subjective Rating of End of Day Dryness With Contact Lens Wear
Participants rate their end of day dryness on a scale from 0 (worst) to 100 (best).
Time frame: Day 5 after dispense with delefilcon A
Subjective Rating of End of Day Dryness With Contact Lens Wear
Participants rate their end of day dryness on a scale from 0 (worst) to 100 (best).
Time frame: Day 7 after dispense with delefilcon A
Subjective Rating of End of Day Dryness With Contact Lens Wear
Participants rate their end of day dryness on a scale from 0 (worst) to 100 (best).
Time frame: Day 21 after dispense with delefilcon A
Subjective Rating of End of Day Dryness With Contact Lens Wear
Participants rate their end of day dryness on a scale from 0 (worst) to 100 (best).
Time frame: Day 28 after dispense with delefilcon A
Subjective Rating of End of Day Dryness With Contact Lens Wear
Participants rate their end of day dryness on a scale from 0 (worst) to 100 (best).
Time frame: 1-month follow up with delefilcon A
Average Lens Wear Time
Average lens wear time is recorded
Time frame: Day 1 after screening with habitual lenses
Average Lens Wear Time
Average lens wear time is recorded
Time frame: Day 3 after screening with habitual lenses
Average Lens Wear Time
Average lens wear time is recorded
Time frame: Day 5 after screening with habitual lenses
Average Lens Wear Time
Average lens wear time is recorded
Time frame: 1-week follow up with habitual lens
Average Lens Wear Time
Average lens wear time is recorded
Time frame: Day 1 after dispense with delefilcon A
Average Lens Wear Time
Average lens wear time is recorded
Time frame: Day 3 after dispense with delefilcon A
Average Lens Wear Time
Average lens wear time is recorded
Time frame: Day 5 after dispense with delefilcon A
Average Lens Wear Time
Average lens wear time is recorded
Time frame: Day 7 after dispense with delefilcon A
Average Lens Wear Time
Average lens wear time is recorded
Time frame: Day 21 after dispense with delefilcon A
Average Lens Wear Time
Average lens wear time is recorded
Time frame: Day 28 after dispense with delefilcon A
Average Lens Wear Time
Average lens wear time is recorded
Time frame: 1-month follow up with delefilcon A
Comfortable Lens Wear Time
Comfortable lens wear time (Time of discomfort - Time of insertion)
Time frame: Day 1 after screening with habitual lenses
Comfortable Lens Wear Time
Comfortable lens wear time (Time of discomfort - Time of insertion)
Time frame: Day 3 after screening with habitual lenses
Comfortable Lens Wear Time
Comfortable lens wear time (Time of discomfort - Time of insertion)
Time frame: Day 5 after screening with habitual lenses
Comfortable Lens Wear Time
Comfortable lens wear time (Time of discomfort - Time of insertion)
Time frame: 1-week follow up with habitual lens
Comfortable Lens Wear Time
Comfortable lens wear time (Time of discomfort - Time of insertion)
Time frame: Day 1 after dispense with delefilcon A
Comfortable Lens Wear Time
Comfortable lens wear time (Time of discomfort - Time of insertion)
Time frame: Day 3 after dispense with delefilcon A
Comfortable Lens Wear Time
Comfortable lens wear time (Time of discomfort - Time of insertion)
Time frame: Day 5 after dispense with delefilcon A
Comfortable Lens Wear Time
Comfortable lens wear time (Time of discomfort - Time of insertion)
Time frame: Day 7 after dispense with delefilcon A
Comfortable Lens Wear Time
Comfortable lens wear time (Time of discomfort - Time of insertion)
Time frame: Day 21 after dispense with delefilcon A
Comfortable Lens Wear Time
Comfortable lens wear time (Time of discomfort - Time of insertion)
Time frame: Day 28 after dispense with delefilcon A
Comfortable Lens Wear Time
Comfortable lens wear time (Time of discomfort - Time of insertion)
Time frame: 1-month follow up with delefilcon A
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