Cortical Excitability and Role of rTMS in Cannabis Use Disorder

Early Phase 1UnknownNCT04106336

Assiut University60 enrolled

Overview

Repetitive transcranial magnetic stimulation (rTMS) and cortical excitability have a role in cannabis use disorder

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Cannabis Use Disorder, Moderate

Interventions

rTMSDEVICE

Repetitive transcranial magnetic stimulation (rTMS) will be done for cannabis addict

Eligibility

Sex: MALEMin age: 18 YearsMax age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * 18to 50 years of age * cannabis use disorder according to DSM 5 definition * clear consent to participate in study Exclusion Criteria: * cardiac peacemaker * metal implant in the head as participate will be applied to magnetic field of TMS * current intake of any medication affect cognition (as anti psychotic and anti epileptic) * current history of neurological , psychiatric or general medical disease .current or previous drug (other than cannabis )or alcohol abuse or participation in another trial during the past 8 weeks . * age younger than 18 and older than 50 years

Outcomes

Primary Outcomes

Determination of role of rTMS for reducing cannabis craving

Incidenc of cannabis craving after rTMS

Time frame: 1 year

Secondary Outcomes

Estimation of cortical excitability in cannabis addict

Incidence of cannabis craving after cortical excitability

Time frame: 1 year

Data from ClinicalTrials.gov

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