This project will study the effect of oxytocin on hemodynamics in patients undergoing laparoscopic myomectomy, and how to prevent and manage such hemodynamic changes effectively.It provides a reference for the rational use of oxytocin in clinical practice, which can not only effectively contract the uterus and reduce bleeding, but also reduce the influence on hemodynamics.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
80
During the laparoscopic hysteromyomectomia operation, different doses of oxytocin was used with different routs.
the Affiliated Hospital of Yangzhou University
Yangzhou, Jiangsu, China
RECRUITINGChanges of traditional hemodynamic parameters after oxytocin use during laparoscopic hysteromyomectomia.
Parameters including SBP, DBP, MAP (mmHg) were measured by a Mostcare hemodynamic monitor.
Time frame: "before induction", "before incision", "before oxytocin intramuscular injection", and "20 sec, 40 sec, 60 sec, 80 sec, 100 sec, 120 sec, 140 sec, 160 sec,180 sec after oxytocin intramuscular injection".
Changes of traditional hemodynamic parameters after oxytocin use during laparoscopic hysteromyomectomia.
HR (beats/min) was measured by a Mostcare hemodynamic monitor.
Time frame: "before induction", "before incision", "before oxytocin intramuscular injection", and "20 sec, 40 sec, 60 sec, 80 sec, 100 sec, 120 sec, 140 sec, 160 sec,180 sec after oxytocin intramuscular injection".
Changes of volume management parameters after oxytocin use during laparoscopic hysteromyomectomia.
SVV (%) was measured by a Mostcare hemodynamic monitor.
Time frame: "before induction", "before incision", "before oxytocin intramuscular injection", and "20 sec, 40 sec, 60 sec, 80 sec, 100 sec, 120 sec, 140 sec, 160 sec,180 sec after oxytocin intramuscular injection".
Changes of volume management parameters after oxytocin use during laparoscopic hysteromyomectomia.
SVRI (dynes-sec/cm-5) was measured by a Mostcare hemodynamic monitor.
Time frame: "before induction", "before incision", "before oxytocin intramuscular injection", and "20 sec, 40 sec, 60 sec, 80 sec, 100 sec, 120 sec, 140 sec, 160 sec,180 sec after oxytocin intramuscular injection".
Changes of volume management parameters after oxytocin use during laparoscopic hysteromyomectomia.
CI (l/min/m2) was measured by a Mostcare hemodynamic monitor.
Time frame: "before induction", "before incision", "before oxytocin intramuscular injection", and "20 sec, 40 sec, 60 sec, 80 sec, 100 sec, 120 sec, 140 sec, 160 sec,180 sec after oxytocin intramuscular injection".
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Changes of volume management parameters after oxytocin use during laparoscopic hysteromyomectomia.
CO (l/min) was measured by a Mostcare hemodynamic monitor.
Time frame: "before induction", "before incision", "before oxytocin intramuscular injection", and "20 sec, 40 sec, 60 sec, 80 sec, 100 sec, 120 sec, 140 sec, 160 sec,180 sec after oxytocin intramuscular injection".