To determine how often embryos reported to be abnormal by preimplantation genetic testing result in liveborn infants. To evaluate whether the pregnancies that result from these embryos are higher risk for complications and whether the resulting babies have higher risk for health or developmental issues in the first five years after birth.
Genetic testing modality and results will be recorded Pregnancy per transfer will be recorded Patients in the study agree to provide medical records of their pregnancy. Any genetic testing or fetal testing will be carefully reviewed and recorded by the study team. For patients with live births, pediatric records will be collected for up to 5 years. As well as surveys for developmental milestones. There is no financial compensation for study participants
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
300
Other than choice of embryo for transfer, all other medical interventions will be standard of care protocols
Standard of Care Protocol
Stanford Fertility and Reproductive Medicine Center
Sunnyvale, California, United States
RECRUITINGPregnancy Rate
Number participants who undergo embryo transfers that lead to a positive pregnancy test
Time frame: 3 years
Live birth rate
Number participants who conceive after embryo transfer and have a live birth.
Time frame: 4 years
Obstetric complications
Number of participants who have a maternal of fetal complication after embryo transfer
Time frame: 4 years
Pediatric Development
Number of newborns and children who have abnormal pediatric development at 3 months, 2 years and 5 years following birth
Time frame: 7 years 3 months
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