REtinaL Imaging & Ambulatory BLood PrEssure

University of Edinburgh591 enrolled

Overview

High blood pressure is a common condition which generally does not have any symptoms. Its estimated that around one third of people with high blood pressure do not know they have it. The back of the eye called the retina is one of the few places in the human body allowing easy observation of blood vessels. This study aims to see if simple non-invasive imaging of the blood vessels of the retina will highlight people with high blood pressure.

This will be a prospective, single centre study recruiting patients who are attending the ambulatory blood pressure clinic at the Western General Hospital. Suitable patients will be approached, and if they consent will have pictures of the back of each of their eyes taken. These pictures will then be reviewed, with certain measurements taken of the small blood vessels which can been seen at the back of the eye. These measurements will then be compared to the participants blood pressure readings to see if they might accurately correlate to blood pressure.

Study Type

OBSERVATIONAL

Enrollment

591

Conditions

Hypertension Blood Pressure

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Attending ambulatory blood pressure clinic * Able to undertake ambulatory BP measurement * Able to undertake single clinic-based BP measurement * Able to undergo UWF retinal imaging with a SLO * Aged 18 to 90 * Able to give informed consent Exclusion Criteria: * People with known history of retinal surgery * People under the age of 18 years. * People that cannot: manoeuvre themselves to the SLO unaided, sit upright in a chair or wheelchair or position themselves comfortably for imaging. * People with epilepsy

Locations (1)

Clinical Research Centre, Western General Hospital

Edinburgh, City Of Edinburgh, United Kingdom

Outcomes

Primary Outcomes

Does retinal arteriovenous ratio correlate to systolic blood pressure

Retinal arteriovenous ratio (as measured by ultra-wide field imaging) will be correlated to mean daytime systolic blood pressure (as measured by 24-hour ambulatory blood pressure monitoring)

Time frame: 1 day

Secondary Outcomes

Does retinal arteriovenous ratio correlate to clinic systolic blood pressure

Retinal arteriovenous ratio (as measured by ultra-wide field imaging) will be correlated to clinic systolic blood pressure.

Time frame: 1 day

Data from ClinicalTrials.gov

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