Phase 1 study that assesses the effect of BMS-963272 on exposure of rosuvastatin in healthy participants
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
28
Specified dose on specified days
Specified dose on specified days
PRA Health Sciences - Salt Lake
Salt Lake City, Utah, United States
Maximum concentration (Cmax)
Time frame: up to Day 10
Area under the plasma concentration-time curve from time 0 to the last quantifiable concentration AUC(0-T)
Time frame: up to Day 10
Area under the plasma concentration-time curve extrapolated to infinity AUC (INF)
Time frame: up to Day 10
Incidence of Adverse Events (AEs)
Time frame: Approximately 50 days
Number of significant changes in lab assessments of blood serum
Time frame: Approximately 50 days
Number of significant changes in lab assessments of blood
Time frame: Approximately 50 days
Number of significant changes in lab assessments of urine
Time frame: Approximately 50 days
Blood pressure
Time frame: Approximately 50 days
Body temperature
Time frame: Approximately 50 days
Respiratory rate
Time frame: Approximately 50 days
Number of Participants with abnormal physical examination findings
Time frame: Approximately 50 days
Heart rate
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Time frame: Approximately 50 days
Number of participants with 12-lead Electrocardiogram (ECG) Abnormalities
Time frame: Approximately 50 days