Effectiveness if Premedication With Single Dose Piroxicam and Prednisolone After a Single Visit Root Canal Treatment .

Dow University of Health Sciences60 enrolled

Overview

Two drugs (Piroxicam and Prednisolone)are being compared for post operative endodontic pain after a single visit root canal treatment for 74 hours.

To evaluate effectiveness of single dose premedication with piroxicam(20mg) and prednisolone(20mg) on post endodontic pain after a single visit root canal treatment . patient will be recalled every day for 4 days to know the pain scale using visual analogue scale .

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Post-operative Endodontic Pain

Interventions

Piroxicam 20 mgDRUG

Piroxicm is from oxicam family of anti inflammatory drug that inhibits prostaglandin synthesis and effectively lower pain threshold levels

prednisolone 20 mgDRUG

prednisolone is from steroid family of anti inflammatory drug that inhibit arachidonic acid and effectively lowers the pain

Eligibility

Sex: ALLMin age: 20 YearsMax age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Patient ages from 20-40 years(28). 2. Single rooted tooth with symptomatic irreversible pulpitis. 3. With no analgesic or anti-inflammatory drug taken within a week period before procedure. Exclusion Criteria: 1. Patients presenting with any systemic disease 2. Patients already taking premedication for endodontic pain. 3. Pregnant or lactating patients. 4. Multirooted teeth. 5. Teeth with Pulpal necrosis. 6. Previously treated or initiated root canal treatment. 7. Patient presenting with allergy due to drug

Locations (1)

DUHS

Karachi, Sindh, Pakistan

Outcomes

Primary Outcomes

post operative pain

post operative pain will be measured after single visit endodontic treatment using visual analog scale with readings 1 to 10 from 24 hours till 76 hours

Time frame: 76 hours

Data from ClinicalTrials.gov

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