This study evaluates acute ingestion of the dietary supplement Resync on blood nitrate/nitrite concentrations in a sample of men and women. This will be a crossover trial in which participants take all 4 conditions: 1) 7.5g Resync, 2) 15g Resync, 3) 20g Resync+collagen, 4) placebo.
The product known as Resync contains a blend of nitrate-rich foods including beetroot, red spinach, turmeric, ginger root, and aronia berry extracts. Resync is sold commercially and marketed as an ergogenic aid and/or exercise recovery aid. Manufacturers of Resync recommend users take this product 60-90 minutes before an athletic event or 30-90 minutes after exercise. Resync bases these claims on prior studies investigating the individual ingredients' abilities to increase blood nitrate/nitrite levels; however, there are no clinical trials on the finished product itself. The purpose of this pilot study is to determine the impact of acute, single ingestion of Resync products on blood nitrate/nitrite concentration in a sample of men and women. This will be a crossover trial in which participants take all 4 conditions: 1) 7.5g Resync, 2) 15g Resync, 3) 20g Resync+collagen, 4) placebo.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Enrollment
20
The product known as Resync contains a blend of nitrate-rich foods including beetroot, red spinach, turmeric, ginger root, and aronia berry extracts. Resync is sold commercially and marketed as an ergogenic aid and/or exercise recovery aid.
17g Collagen + 2g Resync + 1g Carbohydrate
12oz water + food coloring
Center for Nutraceutical and Dietary Supplement Research
Memphis, Tennessee, United States
Change in blood nitrate+nitrite levels from daily baseline with 7.5g Resync
We will determine the change in daily blood nitrate+nitrite from the daily baseline blood nitrate+nitrite with 1 serving (7.5g) of Resync. Resync powder will be mixed with 12oz of water.
Time frame: 75-minutes post supplement ingestion
Change in blood nitrate+nitrite levels from daily baseline with 15g Resync
We will determine the change in daily blood nitrate+nitrite from the daily baseline blood nitrate+nitrite with 2 servings (15g) of Resync. Resync powder will be mixed with 12oz of water.
Time frame: 75-minutes post supplement ingestion
Change in blood nitrate+nitrite levels from daily baseline with 20g Resync+Collagen
We will determine the change in daily blood nitrate+nitrite from the daily baseline blood nitrate+nitrite with 1 serving (20g) of Resync+Collagen. This blend contains approximately 17g of collagen, 2 g of Resync, and 1g carbohydrates. Resync+Collagen powder will be mixed with 12oz of water.
Time frame: 75-minutes post supplement ingestion
Change in blood nitrate+nitrite levels from daily baseline with placebo.
We will determine the change in daily blood nitrate+nitrite from the daily baseline blood nitrate+nitrite with 12oz of food colored water. A red food dye will be used to match coloring of supplements.
Time frame: 75-minutes post supplement ingestion
Change in systolic blood pressure from daily baseline with 7.5g Resync
We will determine the change in daily systolic blood pressure with supplementation from the daily baseline systolic blood pressure with 1 serving (7.5g) of Resync. Resync powder will be mixed with 12oz of water.
Time frame: 75-minutes post supplement ingestion
Change in systolic blood pressure from daily baseline with 15g Resync
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We will determine the change in daily systolic blood pressure with supplementation from the daily baseline systolic blood pressure with 2 servings (15g) of Resync. Resync powder will be mixed with 12oz of water.
Time frame: 75-minutes post supplement ingestion
Change in systolic blood pressure from daily baseline with 20g Resync+Collagen
We will determine the change in daily systolic blood pressure with supplementation from the daily baseline systolic blood pressure with 1 serving (20g) of Resync+Collagen. This blend contains approximately 17g of collagen, 2 g of Resync, and 1g carbohydrates. Resync+Collagen powder will be mixed with 12oz of water.
Time frame: 75-minutes post supplement ingestion
Change in systolic blood pressure from daily baseline with placebo
We will determine the change in daily systolic blood pressure with supplementation from the daily baseline systolic blood pressure with 12oz of food colored water. A red food dye will be used to match coloring of supplements.
Time frame: 75-minutes post supplement ingestion
Change in diastolic blood pressure from daily baseline with 7.5g Resync
We will determine the change in daily diastolic blood pressure with supplementation from the daily baseline diastolic blood pressure with 1 serving (7.5g) of Resync. Resync powder will be mixed with 12oz of water.
Time frame: 75-minutes post supplement ingestion
Change in diastolic blood pressure from daily baseline with 15g Resync
We will determine the change in daily diastolic blood pressure with supplementation from the daily baseline diastolic blood pressure with 2 servings (15g) of Resync. Resync powder will be mixed with 12oz of water.
Time frame: 75-minutes post supplement ingestion
Change in diastolic blood pressure from daily baseline with 20g Resync+Collagen
We will determine the change in daily diastolic blood pressure with supplementation from the daily baseline diastolic blood pressure with 1 serving (20g) of Resync+Collagen. This blend contains approximately 17g of collagen, 2 g of Resync, and 1g carbohydrates. Resync+Collagen powder will be mixed with 12oz of water.
Time frame: 75-minutes post supplement ingestion
Change in diastolic blood pressure from daily baseline with placebo
We will determine the change in daily diastolic blood pressure with supplementation from the daily baseline diastolic blood pressure with 12oz of food colored water. A red food dye will be used to match coloring of supplements.
Time frame: 75-minutes post supplement ingestion
Change in heart rate from daily baseline with 7.5g Resync
We will determine the change in daily heart rate with supplementation from the daily baseline heart rate with 1 serving (7.5g) of Resync. Resync powder will be mixed with 12oz of water.
Time frame: 75-minutes post supplement ingestion
Change in heart rate from daily baseline with 15g Resync
We will determine the change in daily heart rate with supplementation from the daily baseline heart rate with 2 servings (15g) of Resync. Resync powder will be mixed with 12oz of water.
Time frame: 75-minutes post supplement ingestion
Change in heart rate from daily baseline with placebo
We will determine the change in daily heart rate with supplementation from the daily baseline heart rate with 12oz of food colored water. A red food dye will be used to match coloring of supplements.
Time frame: 75-minutes post supplement ingestion
Change in heart rate from daily baseline with 20g Resync+Collagen
We will determine the change in daily heart rate with supplementation from the daily baseline heart rate with 1 serving (20g) of Resync+Collagen. This blend contains approximately 17g of collagen, 2 g of Resync, and 1g carbohydrates. Resync+Collagen powder will be mixed with 12oz of water.
Time frame: 75-minutes post supplement ingestion