Pediatric hypoparathyroidism is an orphan disease. Conventional management combines native and active vitamin D, calcium supplementation and sometimes phosphate binders, with the risk of long term hypercalciuria, nephrocalcinosis and further renal impairment. The use of teriparatide has been reported in adults (daily or bi-daily subcutaneous infusions) and in children (rather continuous subcutaneous infusion) as second-line therapy. The objective of this study is to obtain efficacy and safety data on the use of teriparatide in children with hypoparathyroidism to improve our knowledge of their management.
Study Type
OBSERVATIONAL
Enrollment
9
To compare serum calcium concentrations results in patients with hypoparathyroidism before and three months after initiation of teriparatide therapy
Service de Néphrologie, Rhumatologie et Dermatologie Pédiatriques - Hôpital Femme Mère Enfant
Bron, France
RECRUITINGSerum calcium concentration
Time frame: 3 months after treatment initiation
Serum calcium concentration
Time frame: 1 month after treatment initiation
Serum calcium concentration
Time frame: 6 months after treatment initiation
Serum calcium concentration
Time frame: 12 months after treatment initiation
Serum calcium concentration
Time frame: 3 years after treatment initiation
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