Consecutive patients with high grade aortic stenosis undergoing transcatheter aortic valve replacement (TAVR) with a self-expanding valve (Medtronic CoreValve Evolut R® or Edwards Sapien S3®) without pre-existing pacemaker devices are eligible for inclusion. During the TAVR procedure, an electrophysiologic study including measurements of infranodal conduction times (HV-interval before and after valve implantation) will be performed. Electrocardiograms before TAVR, before discharge, after 30 days and after 12 months will be analyzed regarding new onset LBB and the occurrence of high-degree AV block (HAVB) .
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
200
For the purpose of obtaining intracardiac measurements, the quadripolar diagnostic catheter used as temporary pacemaker wire (5F, Woven, Boston Scientific) during TAVR was retracted from the apex and positioned at the His bundle to measure HV- and AH-intervals.
Universitätsklinikum des Saarlandes
Homburg, Saarland, Germany
RECRUITINGHigh-degree AV block
Occurence of high-degree AV block necessitating a pacemaker implantation during follow up
Time frame: 24 months
Persistence of left bundle-branch block
Persistence of new onset left bundle branch-block following TAVR procedure
Time frame: 24 months
Differences between implanted valve types on ifranodal conduction
Time frame: 24 months
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