Retrospective study that aims to examine the presence of acute kidney injury (AKI) during major abdominal surgery, non- cardiac surgery. Using clinical and biochemical data in order to establish AKI frequency and risk factors.
Ethical approval was submitted and approved by the regional ethical committee, Etisk prövningsnämnd Uppsala, # 2017/418. Patients were selected from the time span of april 2016 to september 2017. The investigators identified 499 patients that had undergone any of the selected procedures. The procedures were, pancreatic resection, HIPEC surgery in colorectal setting, gynecological debulking in metastasized ovarian cancer, and liver resection. The risk of acute kidney injury (AKI) by the KDIGO definition during the postoperative period will be estimated in the group as a whole, and for each type of surgery separately. In addition the data will be stratified by sex to investigate systematic gender disparities or physiological differences. Length of stay, thirty day and sixty day mortality will secondary endpoints.
Study Type
OBSERVATIONAL
Enrollment
499
Incidence of AKI
Frequency of AKI as defined by KDIGO
Time frame: the first 24- 72 hours postop
Mortality
30, 60, and 360 day mortality rate
Time frame: 30, 60 and 360 days postoperatively
Major Adverse Kidney Events
Renal composite outcome according to Major Adverse Kidney Events (MAKE)
Time frame: 30, 60 and 360 days postoperatively
Fluid balance
Fluid balance during surgery, and the first postoperative days.
Time frame: 24-72h
Electrolyte disturbances
Any electrolyte disturbance.
Time frame: 24-72h
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