Total hip arthroplasty refers to the replacement of the femoral head and acetabulum damaged by disease or trauma with an artificial hip joint, thereby restoring joint activity and original function. Acute kidney injury is a common complication after total hip arthroplasty. Previous studies have shown that the incidence of acute kidney injury after hip replacement is as high as 21.9%. Acute kidney injury has become a global safety issue, and the occurrence of acute kidney injury can lead to an increase in hospital stay, medical costs and increased risk of death.There is currently no global survey of the incidence of AKI, and only a number of studies have been conducted on specific patient groups (eg, inpatients, intensive care units \[ICU\] patients or children) due to differences in study design and definition of acute kidney injury.
The incidence and prevalence of different studies vary widely, ranging from 0.32% to 44.30%. There are few studies on the risk factors associated with acute kidney injury after total hip arthroplasty, and early acute kidney injury is often overlooked due to the limitations of the current KDIGO-based diagnostic method. Therefore, it is particularly important for clinicians to understand the risk factors for postoperative acute kidney injury .
Study Type
OBSERVATIONAL
Enrollment
1,500
The Affiliated Hospital of Xuzhou Medical University
Xuzhou, Jiangsu, China
RECRUITINGIncidence and outcome of AKI after joint replacement
AKI can be diagnosed if one of the following conditions is true: (1) Serum creatinine increases by ≥26.5 μmol/L (0.3 mg / dl) within 48 h; (2)Serum creatinine rises more than 1.5 times of the baseline value, and is significantly or presumably the above situation occurred within 7 days;
Time frame: Within 7 days after surgery
Possible risk factors for AKI after joint replacement
Patient's age, gender, height, weight
Time frame: 1 day before surgery
Intraoperative fluid volume and infusion type
Record the total amount of infusion and infusion type of during surgery
Time frame: during sugery and within 7days after surgery
Hemodynamic changes
Focus on the fluctuation of mean arterial pressure
Time frame: during sugery and within 7days after sugery
Factors related to anesthesia
Record the type and dose of anesthetic used in the procedure
Time frame: during sugery and within 7days after sugery
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